Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease that usually affects infants and very young children. In rare cases it can affect adolescents and adults. HLH affects approximately one in every one million children.
Patients with HLH have an abnormally regulated immune system, and specific white blood cells, called macrophages, grow abnormally and accumulate in the body's organs, including the liver, spleen, bone marrow, central nervous system and skin.
There are two main types of HLH: primary and secondary. Primary HLH, also known as familial or relapsing HLH, is an inherited condition. Affected individuals may have an abnormality in a gene that is important in regulation of immune response; some of these gene defects are now known and can be detected. A similar illness, called secondary HLH, may be triggered by certain types of infection, auto-immune diseases and/or by cancer. The treatment of HLH includes chemotherapy. For some patients, bone marrow transplantation is recommended.
**taken from Children's Hospital Boston**
Great information about that dangerous diseases. That is really awful. Really life-threatening factors are involved in it.
ReplyDeleteAlthough blood cells may contain infectious agents, so infected individuals can attack the blood cells from macrophages in the benefit, but also the possibility of hermaphroditic is conducive to an infectious agent. Hermaphroditic macrophages in bacterial cells can be accessed from the intake of nutrients, or hermaphroditic macrophages, can reduce the bacterial killing activity, it kills cells attack them.
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